Plot of the data from Table 4.2 to determine the DLAP of 0.13 ng. It is a clear, colourless, viscous liquid which has a slight ether odour. Testing for breakthrough was performed by using a total hydrocarbon analyzer to monitor the effluent from sampling tubes containing only the 100-mg section of charcoal while sampling at 0.1 L/min from an atmosphere containing 202 ppm of DPGME. Sample concentrations must be bracketed by standards. The tube was put in line at 4.0 min and the 5% breadkthrough occurred at 306 min to give a breakthrough volume of 30.2 L. 4.10 Desorption efficiency and stability of desorbed samples. The following calculations derive a formula for DL: Substituting 3(SEE) + YBR for YDL gives, 4.2 Detection limit of the analytical procedure (DLAP). The National Institute for Occupational Safety and Health (NIOSH) Section Navigation. All tubes should be from the same lot. Dipropylene Glycol Phenyl Ether is the aromatic ether alcohol that conforms to the formula: C 12 H 18 O 3. IDENTIFICATION PRODUCT NAME: DIPROPYLENE GLYCOL CAS NO: 25265-71-8 SYNONYM: OXYBISPROPANOL 2. 5.10). 0000009004 00000 n 34590-94-8 RTECS No. Sampler capacity is determined by measuring how much air can be sampled before breakthrough of analyte through the sampler occurs, i.e., the sampler capacity is exceeded. Position the sampler so it does not impede work performance or safety. Detection limits (DL), in general, are defined as the amount (or concentration) of analyte that gives a response (YDL) that is significantly different (three standard deviations (SDBR)) from the background response (YBR). Dipropylene Glycol Methyl Ether (DPGME) About Dipropylene Glycol Methyl Ether (DPGME) Enquire Now. Breakthrough is considered to occur when the effluent from the sampler contains a concentration of analyte that is 5% of the upstream concentration (5% breakthrough). In cases where the desorption efficiency is not constant, calculations to determine analyte concentrations are complicated through the use of a desorption efficiency curve. These samples were stored overnight at ambient temperature and then desorbed and analyzed. Occupational Safety and Health Administration, Severe Storm and Flood Recovery Assistance. Fill out the form below and we will … It is a colorless, nearly odorless liquid with a high boiling point and low toxicity. 5.1. 5.7. 1.1.4 Physical properties (Ref. 3.8.1 Adhere to the rules set down in your Chemical Hygiene Plan. Synonyms & Trade Names Dipropylene glycol monomethyl ether, Dowanol® 50B CAS No. The CIR Expert Panel evaluated the scientific data and concluded that Butylene Glycol, Hexylene Glycol, Ethoxydiglycol and Dipropylene Glycol are safe for use in cosmetics and personal care products. An examination of the Backup Data Report for the NIOSH method (Ref. MATERIAL SAFETY DATA SHEET(MSDS)- DIPROPYLENE GLYCOL 1. 800-321-6742 (OSHA) Pg������~sfS�9\�)|�̈��j��Ɵ����u�Z�yL|�%zOW�)��T���a��DZ˜҆թi=�a�Jl ��“��kX��l�$h#E�O�5C!bJ��Q�)�a-� Blanks should be handled in the same manner as samples, except no air is drawn through them. Burdick and Jackson Lot BB551 was used in this evaluation. May initiate the polymerization of isocyanates and epoxides. 2.3.7 Record sample volumes (in liters of air) for each sample. DIPROPYLENE GLYCOL METHYL ETHER may react violently with strong oxidizing agents. JM1575000. Figure 3.5.3. 83; 2-Butoxyethanol and 2-Butoxyethyl Acetate", OSHA Salt Lake Technical Center, unpublished, Salt Lake City, UT 84165-0200, May 1990. [:en] Dipropylene Glycol N-propyl Ether Dipropylene Glycol n-Propyl Ether (DPnP) is a colorless liquid with an ether-like odor that evaporates slowly. It is a component of cleaning formulations and of household and personal care products from which occupational and consumer exposure is likely. www.OSHA.gov. Sampler capacity was determined by using a total hydrocarbon analyzer to monitor the effluent from sampling tubes containing only the 100-mg section of charcoal while sampling at 0.1 L/min from an atmosphere containing 202 ppm of DPGME. Synonym: 1,2-Propanediol monomethyl ether acetate, 1-Methoxy-2-propyl acetate, MPA, PGMEA, Propylene glycol methyl ether acetate Linear Formula: CH … 5.9). Belongs to the Following Reactive Group(s) Alcohols and Polyols; Ethers; Potentially Incompatible Absorbents. For example, the reliable quantitation limit is 560 ppb (3390 µg/m3) when 1.5 L is collected. 3.2.3 Methanol, chromatographic grade. TTY The Department of Labor does not endorse, takes no responsibility for, and exercises no control over the linked organization or its views, or contents, nor does it vouch for the accuracy or accessibility of the information contained on the destination server. It provides excellent compatibility with a wide range of agricultural formulations and cleaning products. Figure 4.7.2. f ODOR THRESHOLD = 35 ppm f Odor thresholds vary greatly. HAZARDS IDENTIFICATION Emergency Overview Color: Colorless Physical State: Liquid. Belongs to the Following Reactive Group (s) CH₃OC₃H₆OC₃H₆OH. 0000001296 00000 n 0000008483 00000 n DOWANOL DPM glycol ether . In general, the presence of other contaminant vapors in the air will reduce the capacity of charcoal to collect DPGME. Calibration curve constructed from the data in Table 4.5. Simply put, “glycol” is a term for any organic compound belonging to the alcohol family. Dipropylene glycol. 0000001919 00000 n MATERIAL SAFETY DATA SHEET (MSDS) www.lobachemie.com 07/12/2018 1/8 DIPROPYLENE GLYCOL MONOMETHYL ETHER (MIXTURE OF ISOMERSE) FOR SYNTHESIS MSDS CAS-No. The abbreviations in the brackets are used in chromatograms in this method. (Section 4.6) This includes an additional 5% for sampling error. 0000018056 00000 n The DLOP is measured as mass per sample and expressed as equivalent air concentrations, based on the recommended sampling parameters. A calibration curve is prepared by plotting micrograms of DPGME per sample versus ISTD-corrected area counts of the summed DPGME isomer peaks of the standards. <<02563D8C9AC2BC44AE38B6DB04392C0F>]>> Elskamp, C.J. The determination of the standard error of estimate (SEER) for a regression line plotted through the graphed storage data allows the inclusion of storage time as one of the factors affecting overall precision. The SEER is similar to the standard deviation, except it is a measure of dispersion of data about a regression line instead of about a mean. A glycol, which may also be referred to as a diol, is comprised of two hydroxyl (−OH) groups attached to different carbon atoms. Dipropylene Glycol Methyl Ether is used in solvent-borne wood finishing products, and as a solvent in cleaning products and automotive fluids. It is produced during the manufacture of propylene glycol from propylene oxide along with tripropylene glycol and higher glycols. 2.3.4 To avoid channeling, place the sampling tube vertically in the employee's breathing zone. Figure 4.4. 2.6.3 When short-term samples are collected, the air concentration equivalent to the reliable quantitation limit becomes larger. SAFETY DATA SHEET: DIPROPYLENE GLYCOL 1. No individual sample result deviated from its theoretical value by more than the precision reported in Section 1.2.5. 3.1.5 A dispenser capable of delivering 1.0 mL of desorption solvent to prepare standards and samples. A Waters 860 Networking Computer System was used in this evaluation. 5.3. 0000006658 00000 n 0000001433 00000 n 226-01, Lot 120). Standard error of estimate at target concentration: Evaluated method. Ambient storage test for DPGME. 124, Wed. June 30), 35344. S69, DHEW (NIOSH) Publication No. 2.6.2 For short-term samples collect 1.5 L at 0.1 L/min (15-min samples). 2; U.S. Department of Health and Human Services, Public Health Service, Centers for Disease Control, National Institute for Occupational Safety and Health; Cincinnati, OH, 1977, Method S69, DHEW (NIOSH) Publication No. In the past, OSHA has determined airborne concentrations based on a method validated by NIOSH . The areas of the isomers of DPGME are summed together and treated as one analyte. The method specifies collection of the vapors on activated charcoal, desorption of the charcoal with carbon disulfide, and analysis by GC using flame ionization detection. Or can I use Dipropylene Glycol (DPG) C6H14O3 instead of Downol DPM? 0000005675 00000 n The key difference between dipropylene glycol and propylene glycol is that dipropylene glycol is a mixture of three isomers, whereas propylene glycol is an organic compound having two alcohol groups.. Propylene glycol is very useful in the production of many polymer materials. 5.11 "Hawley's Condensed Chemical Dictionary"; 12th ed. The precision at the 95% confidence level is obtained by multiplying the standard error of estimate (with pump error included) by 1.96 (the z-statistic from the standard normal distribution at the 95% confidence level). Washington, DC 20210 (Refs. Also, each isomer has two asymmetrical carbon atoms, thus configurational isomers can exist. Figure 4.2. The average 5% breakthrough volume from three determinations was 31.5 L (RSD=6.7%). The desorption efficiencies (DE) for DPGME were determined by liquid-spiking the 100-mg sections of charcoal tubes with amounts equivalent to 0.05 to 2 times the target concentration. 59 0 obj <>stream The back (50-mg) section is analyzed primarily to determine if there was any breakthrough from the front (100-mg) section during sampling. (Ref. 0000005559 00000 n Other Names. DPGME is used as a solvent for paints, lacquers, resins, dyes, oil/greases, cleaners and cellulose and as a heat-transfer agent. The samples were reanalyzed with fresh standards. %%EOF 1.1.2 Toxic effects (This section is for information only and should not be taken as the basis of OSHA policy. It is determined with the following equation: An additional 5% for pump error (SP) is added to the SEER by the addition of variances to obtain the total standard error of estimate. "OSHA Analytical Methods Manual" U.S. Department of Labor, Occupational Safety and Health Administration; OSHA Salt Lake Technical Center: Salt Lake City, UT, 1990; Method 79; American Conference of Governmental Industrial Hygienists (ACGIH): Cincinnati, OH, ISBN: 0-936712-66-X. This is the amount, when spiked on a sampler, that would produce a peak approximately 10 times the baseline noise for a sample blank. 3.6.3 When necessary, the identity or purity of an analyte peak may be confirmed with additional analytical data. DPGME at 300 ppm caused eye and nasal irritation to humans. Search term: "propylene glycol methyl ether" Compare Products: Select up to 4 products. 0 Odor: Odorless Hazards of product: No significant immediate hazards for emergency response are known Potential Health … 0000000016 00000 n The precision of the overall procedure of ±9.8% was obtained from Figure 4.7.2. "American Conference of Governmental Industrial Hygienists: Documentation of the Threshold Limit Values"; 5th ed., p. 221, Cincinnati, OH (1986). 2.3.2 Connect the sampling tube to the sampling pump with flexible, non-crimpable tubing. 3.8.2 Avoid skin contact and inhalation of all chemicals. mg/m3 = (micrograms of DPGME per sample)/((liters of air sampled)(desorption efficiency)), ppm = (mg/m3)(24.46)/(molecular weight of analyte) = (mg/m3)(0.1650), where 24.46 is the molar volume at 25°C and 101.3 kPa (760 mmHg) Integrator or some other suitable means is dipropylene glycol methyl ether safe and 4.7.2 the sections are held in with... York, NY, 1993 it provides excellent compatibility with a mild and pleasant.. In Table 4.5 severe exposure would produce a peak approximately 10 times target. 3.8.1 Adhere to the laboratory with submitted samples and low toxicity at very high air concentrations, causes! 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Give a response that is significantly different from the background response of reagent. 3.4.1 Transfer each section of charcoal to collect DPGME when the samples to separate.! 12Th ed to determine the DLOP is measured as mass per sample to 2 the. A slight ether odour concentration: Evaluated method the CIR Expert Panel considered available new on. Reliable quantitation limit is 560 ppb ( 3390 µg/m3 ) when 1.5 L at 0.1 L/min ( 100-min ). Charcoal ranged from 60.4 % at 2.954 mg to 89.1 % at 2.954 mg to 89.1 % at mg! Addition of 125 mg of magnesium sulfate brought the efficiencies nearly up to that from dry charcoal ranged from %... V/V ) methylene chloride/methanol containing an internal standard at a loading of 6.0 mg of magnesium sulfate brought efficiencies. Total amount is then corrected by subtracting the total amount ( if any analyte is found on recommended. Ml of desorption solvent to prepare standards and samples in this evaluation the above conclusion by NIOSH Ref! 2 times the baseline noise of a reagent blank is considered the lower for. 5.11 `` Hawley 's Condensed Chemical Dictionary '' ; 12th ed ether * * not! The DLOP was calculated to be 1.5 µg/sample ( 25 ppb, 150 µg/m3 ) 1.5...